The 49ers have lost three games in a row, but their season isn't dead yet. Sure, they're in last place in the NFC West, but they're also only two games out of first place and they have four winnable games remaining on their schedule.

With its 35-10 loss at Buffalo on Sunday night, the 49ers have now dropped three straight to sink to 5-7 on the season. The blowout loss also marked the first time since 2015 and just the fourth time in franchise history that San Francisco has lost back-to-back games by 25 points or more.

East Rutherford, NJ — November 24, 2024 — Malik Nabers of the Giants on the bench late in the fourth quarter as the Tampa Bay Buccaneers came to MetLife Stadium and defeated the New York Giants 30-7. Chris Pedota, NorthJersey.com / USA TODAY NETWORK via Imagn Images

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks and NFL predictions

The 2024 NFL Week 13 games end with Sunday Night Football as the Buffalo Bills host the San Francisco 49ers. NFL TV schedule, time and how to watch.

Bills on NBC's Sunday Night Football, the NFL Week 13 schedule and more. More: NFL playoff picture: Chiefs become first team to clinch berth after close win vs. Raiders 2024 NFL Thanksgiving Week 13 schedule of football games Here is the NFL schedule for Week 13.