Trump warned Iran on Sunday that it would experience “the full strength” of the US military if it attacks the United States, reiterating that Washington “had nothing to do” with Israel’s strikes on Tehran.

The president’s remarks came after the deadliest night of the five-day confrontation. Iranian ballistic missiles and drones pierced Israel’s defenses shortly before midnight.

Israel's attack on Iran raises questions like whether the US will get involved, how Iran will respond, and if a wider conflict may be triggered.

Tehran said American bases in the Middle East could face reprisals if the U.S. helped repel Iranian attacks on Israel.

Iranian officials and lawmakers are warning of a withering Iranian retaliatory response against Israel but decision makers in Tehran may need to weigh up a major constraint: the desire to avoid actions that would bring the U.

The already volatile Middle East has plunged into a new and dangerous phase of conflict as Israel and Iran openly traded blows over the past two days

Israeli strikes on Iran and Tehran’s vows of reprisals have brought the two Middle East adversaries closer to an all-out war, which also threatens to draw in the United States, at least to some degree

"This confrontation will not end with last night's limited actions and Iran's strikes will continue, and this action will be very painful and regrettable for the aggressors," Fars reported, citing senior military officials.