The 49ers are 5-7, after having gone 25-9 in the past two seasons, and according to NFL.com, they have just a 10% chance of ...

Should Guerendo start as expected Sunday, it will be just his second start as a running back since he was in the fourth grade ...

The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Get your game on! Whether you’re into NFL touchdowns, NBA buzzer-beaters, world-class soccer goals, or MLB home runs, our app ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

The 49ers have lost three games in a row, but their season isn't dead yet. Sure, they're in last place in the NFC West, but ...

The San Francisco 49ers’ playoff chances aren’t completely erased, but they’re low enough that looking toward next year’s ...

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

With its 35-10 loss at Buffalo on Sunday night, the 49ers have now dropped three straight to sink to 5-7 on the season. The ...

How should you approach Purdy with your Bills vs. 49ers NFL DFS picks? The 49ers have been decimated by injuries throughout ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...