Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A mutation that prevents certain amino acids from entering neurons leads to the cells’ death early in brain development, according to a new study in mice. The findings provide clues to what happens in ...

Thousands of previously “invisible” microproteins—tiny chains of fewer than 100 amino acids—can profoundly change human biology when mutated. A fundamental discovery is overturning decades of ...

Genes hold the recipe for proteins, which are made of amino acids. DNA only has four letters, or nucleotides, and each sequence of three nucleotide bases, or codon, encodes for one amino acid. There ...

Scientists showed that fixed mutations within a viral population most likely stem from how easy it is to acquire that mutation (i.e., mutation accessibility) rather than just its benefit. The ...

Mutations are the raw ingredient of evolution, providing variation that sometimes makes an organism more successful in its environment. But most mutations are expected to be neutral and have no impact ...