The most accurate quantitative model yet for understanding the role of condensin during cell division is also visually stunning. A team of scientists from UT Austin have developed the most accurate ...
The first theoretical model of condensin, a molecular machine involved in packing and unpacking chromosomes, accurately reproduces all known experiments with just two parameters. To scrunch a ...
Chromosome with loops (on the left) and the peak-dip derivative curve of the contact probability (on the right). On large and small scales, chromosome folding differs significantly due to the ...
The Telomere-to-Telomere (T2T) consortium, co-led by UC Santa Cruz Genomics Institute Associate Director Karen Miga and National Institutes of Health Genomics Research Institute Senior Investigator ...
A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...
We have developed a theoretical model for evaluating radiation-induced chromosomal exchanges by explicitly taking into account interphase $({\rm G}_{0}/{\rm G}_{1})$ chromosome structure, nuclear ...
This is a preview. Log in through your library . Abstract We have used light microscopy and serial thin-section electron microscopy to visualize intermediates of chromosome decondensation during G1 ...
Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...