First reported in 1928 by Otto Diels and Kurt Alder, the Diels-Alder reaction is one of the most relevant transformations in organic chemistry. Its capacity to generate six-membered rings enables the ...

In a discovery that might come as a shock—or, at the very least, an electric shock—chemists have found that a properly oriented external electric field can nudge two reagents to hook up with one ...

https://doi.org/10.5325/jpennacadscie.93.2.0118 • https://www.jstor.org/stable/10.5325/jpennacadscie.93.2.0118 Copy URL The synthetic method recently established by ...

A computational study focused on the mechanistic pathway of the SpnF-catalyzed cycloaddition reaction leading to Spinosyn A -- tetracyclic natural insecticide produced by the cells of the bacterium ...

Using computational design and directed evolution, scientists have successfully created a metalloprotein that can catalyze a commonly used organic reaction more efficiently than any known enzyme (Nat.

Chiral dirhodium(II) carboxamidates are highly efficient catalysts for reactions between a variety of aldehydes and activated dienes. Catalyst loadings as low at 0.01 mol % have been realized with ...

Until recently it was assumed that cycloaddition reactions (also widely known as the Diels-Alder reactions) do not occur in nature, since corresponding enzymes were never discovered. However, it was ...