THONOTOSASSA, Fla. — A deadly crash on U.S. Highway 301 in Thonotosassa shut down a portion of the roadway Friday night, causing major traffic delays in the area. The Hillsborough County Sheriff's ...

North Carolina State Highway Patrol said Highway 301 has reopened after a crash between a farm tractor-trailer and a Chevy ...

ORANGEBURG, SC (WIS) - The South Carolina Highway Patrol says a truck overturned Friday, spilling a hazardous chemical onto the Highway 301/Interstate 26 interchange in Orangeburg County. According to ...

One of our area's biggest yard sales begins Friday along U.S. Highway 301 in eastern North Carolina. Vendors will line up along the stretch of highway between Weldon and Dunn to sell antiques, ...

SANTEE, SC (WCIV) — One person is dead after a massive tractor trailer turned over and caught fire. It happened on Highway 301 near Interstate 95 around 2:30 p.m. on Thursday. The accident led ...

A person was struck and killed in what appeared to be a one-car accident at the intersection of U.S. Highway 301 and S.C. Highway 4 late Tuesday night. Officials from the Orangeburg County Sheriff's ...

CLAY COUNTY, Fla. — A deadly crash involving multiple vehicles has all southbound lanes of Highway 301 in Clay County blocked Tuesday morning, the Clay County Sheriff's Office said. The crash happened ...

Four people were killed in a wrong-way crash on Thursday afternoon in Wilson County, the North Carolina Highway Patrol said. It happened about 4:50 p.m. on US 301 near Mobley Road, near Lucama. A ...

HILLSBOROUGH COUNTY, Fla. (WFLA) – A traffic accident involving two Hillsborough deputies has shut down a portion of US Highway 301 in Wimauma. According to deputies, around 1:30 p.m. Friday, the ...