Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Efficacy and Safety of Ibandronate in the Treatment of Opioid-Resistant Bone Pain Associated With Metastatic Bone Disease: A Pilot Study To date, our understanding of the role of receptors and their ...

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

It's fascinating because the receptor is not just sensing chemicals from outside the cell, like food or drugs, but also 'tasting' what's happening inside the cell. This new intracellular pocket could ...

Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no cell surface ...

Ligand-stimulated epidermal growth factor receptor (EGFR) signaling plays fundamental roles in normal cell physiology, such as cell growth, cell proliferation, and cell survival. Deregulation of EGFR ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...