Food restriction and weight loss result in reduced plasma leptin, which is associated with a pleiotropic biologic response. However, because weight loss itself is also associated with changes in ...

Consistent with findings from experimental research in nonhuman primates exposed to early-life stress, children exposed to maltreatment are at high risk of detrimental physical health conditions, such ...

Baltimore, MD - The natural hormone leptin or a component of its signaling pathway can reverse obesity-associated left ventricular hypertrophy (LVH) independent of body weight, a study in mice at ...

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommended marketing authorization for metreleptin (Myalepta, Aegerion Pharmaceuticals BV) for the treatment of ...

When a toddler weighs nearly 100 pounds and he/she is still not satisfied with the quantity he/she takes in, it is not only a case of an indiscriminate eater, but it is also a case of a medical puzzle ...

Benjamin Freitag was always hungry as a child, even after meals, and weighed nearly 100 lbs. by the time he was 3 He was eventually diagnosed with a leptin deficiency, which caused his brain to tell ...

B12 deficiency during pregnancy may predispose children to metabolic problems such as type-2 diabetes, according to research. These findings could lead to a review of current vitamin B12 requirements ...

B12 deficiency during pregnancy may predispose children to metabolic problems such as type-2 diabetes, according to research presented today at the Society for Endocrinology's annual Conference in ...