Leptin is a hormone that is produced in adipocytes and exerts its effects on the brain and several other peripheral tissues. It plays a crucial role in regulating endocrine functions and controlling ...

Baltimore, MD - The natural hormone leptin or a component of its signaling pathway can reverse obesity-associated left ventricular hypertrophy (LVH) independent of body weight, a study in mice at ...

Four years after its discovery, the weight-controlling protein hormone leptin is still making news. At the American Diabetes Association meeting in Chicago June 14, researchers from Amgen Inc. of ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) poses a significant challenge in modern medicine due to its high prevalence. The pathogenesis of MAFLD involves a complex dysmetabolic ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

December 15, 2009 — Investigators have uncovered further evidence that leptin may protect against Alzheimer’s disease (AD), opening the door a little wider for a possible future target for therapeutic ...

Researchers identified how leptin, a hormone from fat cells, fuels estrogen receptor-positive breast cancer. The study found ...

Ask ten people to receive as many different answers on the key to weight loss. From special diets to key exercises to the old adage of “calories in, calories out,” the hypotheses abound. There’s ...

Ciliary Neurotrophic Factor (CNTF) was first characterized as a trophic factor for motor neurons in the ciliary ganglion and spinal cord, leading to its evaluation in humans suffering from motor ...

Studies have shown that serum leptin is positively correlated with percentage body fat in humans. 3 Women exhibit a threefold higher circulating level of leptin than men do, possibly because they have ...