Leptin is a hormone that helps manage energy. It signals to your brain when you need food or when you’re satiated. But, leptin resistance can cause the brain to miss this signal, which may contribute ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Hormone absence or inactivity is common in congenital disease, but hormone antagonism remains controversial. Here, we characterize two novel homozygous leptin variants that yielded antagonistic ...

Obesity has become a global epidemic, and the need for treatment and monitoring for people with obesity is growing.

Researchers have discovered a new population of neurons that is responsive to the hormone leptin. Leptin responsive neurons are important in obesity since leptin is sent to the brain from the body's ...