Leptin, an adipokine that is implicated in the control of food intake via appetite suppression, may also stimulate oxidative stress, inflammation, thrombosis, arterial stiffness, angiogenesis and ...

Most leptin supplements don’t actually contain the hormone leptin. Research is unclear whether these supplements can help you lose weight, but some studies suggest they can influence leptin ...

Researchers have successfully treated two unrelated children with characteristics of leptin dysfunction — including intense hyperphagia, impaired satiety, and severe, early onset obesity — only after ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers ...

Hormone absence or inactivity is common in congenital disease, but hormone antagonism remains controversial. Here, we characterize two novel homozygous leptin variants that yielded antagonistic ...

Leptin is a 167-amino acid protein cytokine that was originally discovered to manage the white fat energy reserves in mice. White fat cells make the protein in amounts depending on their fat load The ...

To keep the human brain supplied with energy when food was scarce, mammals evolved the ability to switch from burning carbohydrates to burning fat in order to preserve skeletal muscle that would ...

Obesity has become a global epidemic, and the need for treatment and monitoring for people with obesity is growing.

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a study has found. Reduced levels of a metabolic hormone known as leptin ...