Leptin is a hormone that helps manage energy. It signals to your brain when you need food or when you’re satiated. But, leptin resistance can cause the brain to miss this signal, which may contribute ...

Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) ...

For years, scientists have pointed to leptin resistance as a possible cause of obesity. Research led by investigators at the University of Cincinnati (UC) Metabolic Diseases Institute, however, found ...

Obesity prevalence continues to increase at an alarming rate, but current therapies are limited by side effects and modest efficacy. Now, writing in Cell Metabolism, Ozcan and colleagues show that ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio The ratio of leptin to adiponectin may be ...

Researchers have uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity: leptin resistance. They found that mice fed a high-fat diet ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, ...

Please provide your email address to receive an email when new articles are posted on . Leptin adjusted fat mass is greater among women who eat more ultraprocessed ...

A paper published in the May issue of Diabetes implicates triglycerides in the mechanism of leptin resistance. These fats, elevated in obesity, are what disrupt the transport of the hormone across the ...

Food restriction and weight loss result in reduced plasma leptin, which is associated with a pleiotropic biologic response. However, because weight loss itself is also associated with changes in ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Figure 1: Body weight gain, food intake and plasma insulin and leptin levels in chow-fed mutant mice and wild-type littermates. Figure 4: a and b, Measures of glucose homeostasis in mutant mice (M) ...