Hormone absence or inactivity is common in congenital disease, but hormone antagonism remains controversial. Here, we characterize two novel homozygous leptin variants that yielded antagonistic ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) poses a significant challenge in modern medicine due to its high prevalence. The pathogenesis of MAFLD involves a complex dysmetabolic ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Obesity has become a global epidemic, and the need for treatment and monitoring for people with obesity is growing.

A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Utreglutide, in multiple ascending doses, caused ...

Leptins belong to a class of adipocyte-originating hormones that have a variety of functions in the regulation of appetite and metabolism, as well as in immune regulation. The lungs are a rich source ...

Researchers discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms. Researchers at Baylor College of Medicine and collaborating ...