Nature

Interferon-β lipofection II. Mechanisms involved in cell death and bystander effect induced by cationic lipid-mediated interferon-β gene transfer to human tumor cells

We evaluated the cytotoxic effects (apoptosis, necrosis and early senescence) of human interferon-β (hIFNβ) gene lipofection. The cytotoxicity of hIFNβ gene lipofection resulted equivalent to that of ...
Nature

Interferon-β lipofection I. Increased efficacy of chemotherapeutic drugs on human tumor cells derived monolayers and spheroids

The aim of this study was to evaluate whether the hIFNβ gene improved the antitumor effect of antineoplastic drugs used as first-line treatment in the management of advanced cancer. Our results ...
Science Daily

Nanosurgery and the fight against cancer

Researchers have succeeded in changing the genetic material of cancer cells using a brand-new transfection method. This breakthrough in nanosurgery opens the door to new medical applications, among ...