Approximately 9.5 million people globally live with type 1 diabetes, a chronic autoimmune disease where T cells from the body ...
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Lysosomal acidity fine-tunes reactive species production in macrophages
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...
New research from Indiana University School of Medicine scientists has revealed that a well-known cancer-fighting gene also ...
Switching off a single enzyme in immune cells protected mice from obesity, type 2 diabetes, and fatty liver disease in a new ...
Working with macrophages, Resolution Therapeutics faces a “unique” manufacturing challenge. They progressively lose cells as they move towards their final product. Damian Marshall, PhD, VP, analytics, ...
An international team led by Monash University and Baylor College of Medicine, Texas, has found "switching off" an enzyme called CaMKK2 in immune cells that drive inflammation prevents diet-induced ...
Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to properly process cholesterol—something that breaks down during ...
Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body maintain healthy cholesterol levels-a significant development that could lead ...
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