Methotrexate belongs to a class of drugs called antimetabolites. This type of drug slows the growth of skin cells or cancer cells and suppresses the immune system. In addition to treating rheumatoid ...

Please provide your email address to receive an email when new articles are posted on . Patients with RA treated with first-line upadacitinib over 5 years had greater reductions in disease activity vs ...

Delaying MTX initiation by 4 weeks after PCV13 vaccination significantly improved humoral responses in patients with RA, without compromising disease control.

Please provide your email address to receive an email when new articles are posted on . Methotrexate use at the pre-arthritis stage of symptoms and subclinical inflammation fails to prevent clinical ...

Methotrexate is widely regarded as the cornerstone drug in RA management, but debate continues on the optimal dosing schedule ...

Methotrexate is the gold standard of care for RA, but it can also disrupt a pregnancy. In states with strict anti-abortion laws, some women with RA cannot get their routine medication easily or ...

The medication methotrexate is used to treat cancer, arthritis, lupus and Crohn’s disease. Patients have reported trouble accessing it after the Supreme Court's ruling on abortion and a number of new ...

The intracellular polyglutamation of methotrexate (MTX) is emerging as a crucial biochemical process in rheumatoid arthritis (RA) therapy. MTX polyglutamates (MTX-PGs) are metabolites formed by the ...

Older patients with chronic kidney disease (CKD) had greater risks for serious adverse events when starting on low-dose methotrexate rather than hydroxychloroquine, a propensity score-matched analysis ...