A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson's ...

Lysoway Therapeutics, Inc., a biotechnology company advancing structure-guided small-molecule modulators of lysosomal ion ...

The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill ...