It is remarkable that cancer chemotherapies, with generally narrow therapeutic windows and possibilities for life-threatening toxicities, are usually dosed according to body-surface area (BSA). The ...
Sept. 16, 2003 — St. John's wort increases metabolism via the cytochrome P450 (CYP) enzyme system 3A4, according to the results of a study published in the Sept. 17 issue of The Journal of the ...
According to commonly accepted criteria, CYP testing separates individuals with polymorphisms into five categories: poor metabolizers (PMs); intermediate metabolizers (IMs); extensive metabolizers ...