Northwestern University professor Hande Ozdinler is hoping to change how ALS is treated, saying the disease is too complex ...

A newly discovered type of mitochondrial self-destruction may make some brain cells vulnerable to ALS, also known as Lou Gehrig’s disease. In mice genetically engineered to develop some forms of a ...

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies ...

Single-cell gene expression patterns in the brain motor and frontal cortex, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for ...

When you take a walk, talk to a friend, or chew a piece of food, motor neurons are behind these movements. Just like other parts of your body, they can become damaged. You may have heard of ALS, ...

Niigata, Japan – our movements are controlled by multiple neural pathways that connect the brain and spinal cord. In particular, neurons in the cerebral cortex send commands to the motor neurons in ...

Primary lateral sclerosis (PLS) is a motor neuron disease variation of ALS (amyotrophic lateral sclerosis) but far more rare. PLS refers to patients who seem to have disruptions with only upper motor ...

Motor neuron disease (MND) is a progressive condition that occurs when certain nerve cells degenerate and die. There are two types of motor neuron cells. The upper motor neuron begins in the brain and ...

A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease. ALS is purely a motor neuron disease; sensory neurons are not affected. 4 ...

Primary lateral sclerosis (PLS) is a rare neurological disorder that affects the motor neurons in the brain and spinal cord, which control movement. It is a form of motor neuron disease (MND). PLS ...