Israel and Iran exchange missile attacks for a third day; nuclear sites hit, death tolls rise, airspace shut, U.S. warns Tehran against retaliation.

Most of those confirmed dead were women and children, according to the authorities, although they have yet to publicly name the victims.

Missiles and projectiles were seen in the skies over Jerusalem and Tel Aviv early on Sunday as Tehran unleashed a fresh attack on Israel which in turn launched an expanded assault on Iran.

DUBAI — Israel unleashed airstrikes across Iran for a third day Sunday and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country. Planned talks on Iran’s nuclear program, which could provide an offramp, were canceled.

The Middle East conflict intensified as Israel conducted airstrikes on Iranian nuclear sites, marking a significant escalation. Iran retaliated with missile attacks on Israel, leading to exchanges of missiles and drones,

At least ten people were killed in Israel overnight, after multiple Iranian missiles evaded the country's advanced defense systems. Explosions rocked Tehran, but casualties weren't immediately clear.

IDF Spokesperson Brig.-Gen. Effie Defrin elaborated that the military's goal in Operation Rising Lion is not to achieve regime change in Iran, but rather to remove Iran's capabilities to annihilate Israel, according to a Sunday afternoon statement.

Onlookers gathered on Saturday at a central Tel Aviv residential building next door to Israel’s defense headquarters that was damaged after it took a hit from what appeared to be shrapnel from an overnight missile barrage from Iran.