90% of people with obesity have leptin resistance – new research has found a mechanism involved and a way to reverse it using ...

Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.

A paper published in the May issue of Diabetes implicates triglycerides in the mechanism of leptin resistance. These fats, elevated in obesity, are what disrupt the transport of the hormone across the ...

Higher leptin levels were associated with chronic widespread pain among patients with RA, even after adjusting for age, BMI, and sex.

However, there may be circumstances where a person develops a resistance to leptin, weakening the body’s reactivity to the hormone. This unfavourable circumstance could result in overeating ...

However, daily leptin shots are both expensive -- costing ... as it improves insulin resistance. Tirzepatide is administered through a weekly injection, potentially reducing the burden and pain ...