Winter Storm Fern is expected to cause significant travel disruptions due to heavy snow and ice across 33 states in the U.S., affecting up to 180 million people, with impacts starting Friday night and continuing through Monday.

"Potentially hundreds of thousands of people may go without electricity and heat for days, one meteorologist said

An arctic blast is expected to bring dangerously cold temperatures and winter weather across the eastern United States this weekend, affecting regions as far south as Florida. High temperatures in western Mass.

Over the weekend, a powerful winter storm is set to impact more than 130 million people across the United States as heavy winter precipitation, strong winds, and bitterly cold temperatures move in, bringing dangerous conditions.

ROCHESTER, Minn. (KTTC) – A potentially historic winter storm is set to impact the southern United States. Winter Storm Watches are already in place for much of the south-central and southeast United States for this upcoming weekend.

A major, widespread winter storm will lash much of the South, Midwest and Northeast with heavy snow likely for tens of millions of people from New Mexico to New England.

Lawrence could get hit with around seven inches of snow over the weekend and face periodic wind chills of negative 20 degrees, according to the National Weather Service. The weather impacts are due to a wide-ranging storm that will hit much of the eastern United States on Friday where forecasts anticipate around 150 million people

The storm will be so extensive, its snow, sleet and freezing rain could stretch more than 1,500 miles from the Plains across the South and into the Northeast. Major travel disruption is a given across its entire footprint.