ORCHARD PARK, NEW YORK - JANUARY 19: Lamar Jackson #8 of the Baltimore Ravens and Josh Allen #17 of the Buffalo Bills embrace after the AFC Divisional Playoff game at Highmark Stadium on January 19, 2025 in Orchard Park, New York. (Photo by Al Bello/Getty Images) Getty Images

Former Buffalo Bills safety Jordan Poyer would it would be the 'fantasy ending' to his career to return to Buffalo for one final season.

The season openers between the Dallas Cowboys and Philadelphia Eagles and Baltimore Ravens-Buffalo Bills and Detroit Lions-Green Bay Packers are among the most intriguing matchups to launch the 2025 NFL campaign.

Every NFL schedule presents unique challenges for teams but we picked the toughest for the Bucs on the 2025 schedule.

The seven prime-time games the Chiefs are in ties an NFL record with the 2023 Buffalo Bills, who ended up being flexed into a prime-time slot in Week 18 to previously set the record. The NFL scheduled the seven prime-time games for the Chiefs due to their loaded schedule of opponents.

The Buffalo Bills’ 2024 season had been complete for less than a month when multiple tentacles of the organization had their first meeting about their annual schedule release video. A year after quarterback Josh Allen appeared in the entire video as a “resident” of the new Highmark Stadium,

The 49ers endured a disappointing 2024 NFL season, but it has set them up for potential success in 2025. San Francisco is playing a fourth-place schedule after finishing last in the NFC West. That set them up with matchups against the Bears, Browns and Giants.

Former Mississippi State wideout Kelly Akharaiyi is turning heads in Buffalo’s camp as an undrafted underdog with real potential.