The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve.

The San Francisco 49ers' dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...

SANTA CLARA, CALIFORNIA - JANUARY 22: Christian McCaffrey #23 of the San Francisco 49ers rushes for a touchdown against the ...

Christian McCaffrey was tearing it up against the Bills before exiting early in the second quarter with a knee injury.

The San Francisco 49ers running back injured the PCL in his knee, an MRI confirmed Monday. San Francisco plans to place ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

Christian McCaffrey and Jordan Mason both landed on IR after the 49ers lost to the Bills in Week 13. Isaac Guerendo will now ...