Fantasy managers may need to proceed with caution before placing San Francisco's offensive players in their lineup this week.

Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

Star pass-catcher George Kittle and the San Francisco 49ers meet the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark ...

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium in Orchard Park, New York, on Sunday, December 1, at ...

"Sunday Night Football" in Week 13 sees the San Francisco 49ers taking on the Buffalo Bills. Here's the latest on a snowy ...

Snow is burying Highmark Stadium ahead of the Dec. 1 matchup between the Buffalo Bills and San Francisco 49ers.

Running back Christian McCaffrey says the 49ers are “hungry” to make a playoff push even with the defending NFC champions ...

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

ORCHARD PARK, N.Y. -- Josh Allen’s latest kneel-down had nothing to do with football.

Highest snow accumulations expected east of Lake Ontario, where some isolated areas could get hit by up to 60 inches of snow.

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...

The Buffalo Bills announced Saturday that they are activating Matt Milano off injured reserve. It puts the linebacker in a ...