San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

The 49ers have revealed their latest injury report before their Sunday Night Football tilt against the Buffalo Bills.

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look ...

Even after Christian McCaffrey’s return to the field, the story surrounding his Achilles injury and the impact it’s having on ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

The 49ers just lost 38-10 to the Green Bay Packers. Here are the 49ers' grades for this performance. QUARTERBACK: C-MINUS.

San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa ...