A patient with rheumatoid arthritis in her 30s who had a left knee that had been ankylosed for 10 years was treated with robotic-arm assisted total knee replacement (RA-TKR) and surgical release of ...

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Precocious puberty, characterised by the early appearance of secondary sexual characteristics, poses challenges in diagnosis and management. Here, we describe a case of precocious puberty diagnosed in ...

Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical ...

Trastuzumab-deruxtecan (T-DXd) is a novel antibody drug conjugate that has improved treatment outcomes in patients with ERBB2-positive cancer, including locally advanced or metastatic gastric and ...

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A man in his 30s with a history of refractory classical Hodgkin’s lymphoma presented with subacute onset asymmetric sensory disturbance, and severe weakness affecting his right more than left hand.

Reed’s syndrome (RS) is a rare autosomal-dominant disorder characterised by multiple cutaneous and uterine leiomyomas, with a strong tendency for renal cell carcinoma (RCC) development. A woman in her ...

Phenotypic plasticity refers to the ability of tumour cells to undergo molecular and phenotypic changes in response to microenvironmental stresses, genetic and epigenetic alterations, or ...

Giant cell tumour (GCT) accounts for 5% of all primary bone tumours. GCT in the distal third of ulna is quite rare. We present a case of recurrent GCT in distal third of ulna with malignant features ...