In phase 2 trials involving patients with stage 2 or 3 fibrosis caused by metabolic dysfunction–associated steatohepatitis (MASH), efruxifermin, a bivalent fibroblast growth factor 21 (FGF21 ...

Hypoxemia occurs early during an attack and, as indicated by the low carbon dioxide tensions, is not the result of overall underventilation. In that regard asthmatic patients act like the group of ...

Christopher Duggan is the director of the Center for Nutrition at Boston Children’s Hospital, a professor of pediatrics at Harvard Medical School, and a professor in the Departments of Nutrition ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

Obicetrapib is a highly selective cholesteryl ester transfer protein inhibitor that reduces low-density lipoprotein (LDL) cholesterol levels. The efficacy and safety of obicetrapib have not been ...

Mycobacterium tuberculosis continues to cause substantial illness globally. The efficacy of BCG revaccination for the prevention of sustained M. tuberculosis infection is unclear. New research ...

Medical House Pupil, Massachusetts General Hospital, 1901; Assistant in Pediatrics, Harvard University; Assistant Physician at the Children's Hospital; Assistant Physician and Pathologist at the ...

Dr. Maxwell Green (Medicine): A 70-year-old man presented to the emergency department of this hospital because of a 6-week history of anorexia, weakness, and weight loss. Six weeks before this ...

Arthur Robin Williams is an associate professor of clinical psychiatry at Columbia University and a research scientist at the New York State Psychiatric Institute. Stephen Morrissey, the ...

The International Agency for Research on Cancer (IARC) classified alcoholic beverages as carcinogenic to humans (Group 1) on the basis of sufficient evidence of causality for seven types of cancer ...

Of the 804 patients who underwent randomization, 403 were assigned to receive mepolizumab and 401 to receive placebo. The annualized rate of moderate or severe exacerbations was significantly ...

Shown are the genetic variants identified in EPO, the gene encoding erythropoietin (EPO), in patients with erythrocytosis. The term cDNA denotes complementary DNA, F female, M male, and NA not ...