Q: My doctor just told me that I’m now considered obese. A week ago, I wasn’t — and I haven’t gained any weight. What’s going ...

Here we summarize recent progress in the biology of leptin, concentrating on its central nervous system (CNS) actions. The product of the ob gene, leptin is a circulating hormone produced by white ...

We report here that the delivery of leptin to the hypothalamus through intracranial gene transfer results in the efficient normalization of body weights in obese mice, using doses of recombinant virus ...

A brain circuit involving leptin allows mice to carry out vital behaviors, such as eating and sleeping, during anxious episodes. A study led by researchers at the University of Cologne and University ...