San Francisco is in desperation mode after back-to-back losses and find itself as a touchdown underdog in Buffalo.

Snow has blanketed Orchard Park, New York, where the Buffalo Bills will play the San Francisco 49ers on Sunday Night Football ...

If you have access to NBC via your TV provider, you can watch Sunday Night Football on your TV or with a TV provider login on ...

Your daily San Francisco 49ers news for Sunday, December 1st, 2024 ...

The Buffalo Bills face a tough challenge against the 49ers in Week 13, but the good news is that Josh Allen and Sean ...

The Buffalo Bills have shared a clip of intense snow covering Highmark Stadium ahead of their game with the San Francisco ...

The Bills are 9-2, their best start since 1992, and with a win would clinch their fifth straight AFC East title.

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, ...

Purdy is officially listed as questionable for the game, though coach Kyle Shanahan said the plan is for him to start on ...

As the 49ers prepare for their Week 13 matchup against the Bills, Brock Purdy will be the signal caller after being listed as ...

The San Francisco 49ers saw their playoff chances plummet following consecutive losses to the Seattle Seahawks and Green Bay ...

Highest accumulations were expected east of Lake Ontario, where some isolated areas could get hit by up to 60 inches of ...