If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

eLife Assessment This valuable study is a detailed investigation of how chromatin structure influences replication origin function in yeast ribosomal DNA, with a focus on the role of the histone ...

Vilgalys, R. and Hester, M. (1990) Rapid Genetic Identification and Mapping of Enzymatically Amplified Ribosomal DNA from Several Cryptococcus Species. Journal of Bacteriology, 172, 4238-4246.

Chemotherapeutics altering DNA topology evoke RNA polymerase I inhibition, rDNA damage and consequent formation of PNAs that segregate persistent rDNA lesions from the active nucleolus, with ...

Since the 1950s, a chemotherapy drug known as 5-fluorouracil has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract.

ABSTRACT: Microorganisms are omnipresent in all environments and play mainly the role of transformers, thanks to the multiple enzymes they are able to produce. In order to valorize fermented foods in ...

This showed that the ribosomal DNA copy number in a person was strongly associated with markers of systemic inflammation that are well known, like the systemic immune-inflammation index (SII), ...

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses. A new study of 500,000 individuals indicates that people who have more ...