The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

San Francisco 49ers linebacker Fred Warner recently revealed that he has been playing through a bone fracture in his ankle, ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

The 49ers brass — Kyle Shanahan, John Lynch, and CEO Jed York chief among them — have not wavered on their commitment to ...

San Francisco 49ers' Trent Williams' wife Sondra has announced the death of their baby son at 35 weeks after losing his twin ...

When it comes to quarterbacks, Kyle Shanahan is extremely picky. He often isn't wild about young quarterbacks who have lots of hype. And when he ...

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

The 49ers' disappointing season took another negative turn in their Week 13 loss to the Bills, and George Kittle addressed ...

Watching NFL games, including Fox broadcasts, is simple with Hulu + Live TV, which includes 90 channels, unlimited DVR ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...