Publishes original research, insights and opinions on evidence-based research. Focuses on the tools, methods, and concepts that are central to practising evidence-based medicine.

Data extraction is the process of a systematic review that occurs between identifying eligible studies and analysing the data, whether it can be a qualitative synthesis or a quantitative synthesis ...

Health technology assessment (HTA) is a multidisciplinary process that uses explicit methods to determine the value of a health technology at different points in its lifecycle.1 ,2 Its aim is to ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...

The introduction of generative large language models (LLMs) has led to the exploration of their use in evidence synthesis tasks, such as literature searches,1 screening,2 3 risk of bias assessment,4 5 ...

Objectives Endometrial cancer (EC) incidence has been rising globally, while mortality has remained stable, particularly in Nordic countries. This study aimed to explore the role of transvaginal ...

There is a recognised knowledge deficit about the absolute size of benefits and harms of treatments among clinicians1 2 restricting the possibility of good quality shared decision-making3 4 and ...

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, ...

Open scholarship practices—often also referred to as open research or open science—are increasingly seen as relevant to the research lifecycle. What open scholarship looks like in practice will ...

Health literacy demands placed on patients and consumers are amplified in low-value care contexts and must be addressed as a system and organisational priority, argue Danielle Muscat and colleagues . ...