An SHBG blood test measures a protein that attaches to sex hormones in your blood. It's usually done if you have symptoms of too much or too little testosterone.

Although SHBG binds 3 hormones, the hormone that's critical in this test is testosterone. SHBG controls the amount of testosterone that your body tissues can use.

Dec 24, 2025 · Changes to SHBG (sex hormone binding globulin) can impact other hormones in your body. Find out what high levels and low levels mean.

May 19, 2025 · Because SHBG primarily binds testosterone, symptoms of abnormally high or low testosterone levels in both men and women may warrant an SHBG test. This test requires a …

Sex hormone-binding globulin (SHBG) is a major carrier protein for sex steroids in the blood. Determination of SHBG concentrations is useful in the investigation of cases of suspected …

Learn what sex hormone-binding globulin (SHBG) is, how it regulates testosterone & estrogen, and why SHBG testing is crucial for diagnosing hormone imbalances like PCOS & low …

SHBG has a half-life of about seven days and is produced mainly by the liver. Its synthesis and secretion are regulated by estrogen. 5,6 SHBG serum concentrations depend on the extent, …

Nov 22, 2021 · What Is the Sex Hormone Binding Globulin Test? The sex hormone binding globulin test is an SHBG blood test. Your doctor will use this test to measure the levels of the …

Oct 11, 2025 · Doctors order the SHBG test mainly to evaluate hormone imbalances or to assess conditions like infertility, polycystic ovary syndrome (PCOS), or liver disease. Usually, no …

Apr 24, 2025 · Measuring SHBG shows how much free active sex hormone is available for your body to use. A free androgen index is calculated from these results and is valuable in …