Grignard Reaction, Mechanism, Reagent and Cheat Sheet
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Grignard Reaction, Mechanism, Reagent and Cheat Sheet
Grignard Reaction involves an Organometallic R-X attacking aldehydes or ketones to form alcohols in chain elongation reactions. Cheat Sheet
Feb 21, 2020
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SOLVED:Grignard reagents are powerful nucleophiles and strong bases. They act as nucleophiles by attacking a variety of compounds including saturated and unsaturated carbon atoms. Examples of reaction on saturated carbon include oxiranes (epoxides) which form alcohols as the final product. When R and R^'=H, product is 1^∘ alcohol. When R and R^'= Alkyl group, product is 3^∘ alcohol. When one R or R^' is alkyl, product is 2^∘ alcohol. Product. Here, the nucleophile C6 H5^- attacks (a) C1 (b) C2 (
SOLVED:Grignard reagents are powerful nucleophiles and strong bases. They act as nucleophiles by attacking a variety of compounds including saturated and unsaturated carbon atoms. Examples of reaction on saturated carbon include oxiranes (epoxides) which form alcohols as the final product. When R and R^'=H, product is 1^∘ alcohol. When R and R^'= Alkyl group, product is 3^∘ alcohol. When one R or R^' is alkyl, product is 2^∘ alcohol. Product. Here, the nucleophile C6 H5^- attacks (a) C1 (b) C2 (
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Explain the following reaction with a suitable example. Gatterman reaction - Chemistry | Shaalaa.com
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